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Polynucleotides

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Polynucleotides

Polynucleotides

Commonly referred to as the “Salmon Sperm Facial”, this treatment features highly purified DNA fragments that activate the skin’s natural healing processes at a cellular level. With powerful anti-inflammatory properties, it repairs and regenerates the skin without changing facial shape or adding volume.

By supporting collagen and elastin production, polynucleotides improve skin elasticity, firmness, and overall texture, leaving the skin smoother, more resilient, and radiant.

Suitable for all skin types, polynucleotides are a versatile treatment that can be used to address a variety of common skin concerns.

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Benefits of Polynucleotides

Skin Repair and Regeneration

Great for dry, tired, or dull skin

Improves firmness and elasticity, circulation, puffiness and dark circles, without adding volume.

Ideal for photo-aged and sun-damaged skin

Under-eyes, face, peri-oral, hands, neck & décolletage

Calms inflammation and redness and supports recovery after procedures such as lasers, chemical peels, microneedling

Improved skin strength, elasticity, and thickness over time

Helpful for inflamed acne, redness and reactive skin

Doesn’t add volume or change facial features

Treatment Overview

Treatment Time

10-15 minutes

Discomfort Level

Minimal, topical numbing

Downtime

6-12 hours

Protocol

3 sessions, 2-4 weeks apart

Maintenance

1 session every 3 months

Polynucleotides - FAQs

What is the difference between polynucleotides and other skin boosters?

Both types of treatments improve skin quality but work via different mechanisms and materials.

  • Polynucleotides are DNA-based and focus on cellular repair and anti-inflammation.
  • Profhilo and other hyaluronic acid-based skin boosters focus on hydration and skin remodelling.

 

A unique advantage of polynucleotides is their suitability for treating delicate areas like the under-eye region, where Profhilo cannot be used.

Polynucleotides have a very high safety profile. To date, there have been no adverse reactions to the product. However, like any medical procedure, treatment should only be administered by a qualified medical professional in a sterile environment.

We normally apply an anaesthetic numbing cream prior to the treatment to reduce any discomfort. Overall, polynucleotides treatment is generally well tolerated.

Yes, once acne is stabilised and well controlled. Polynucleotides are particularly beneficial for healing, reducing redness, improving scarring, and supporting overall skin recovery. They are best used as part of a comprehensive acne treatment plan rather than as a standalone solution.

  • Initial course: 3 treatments, spaced 2-4 weeks apart.
  • Maintenance: 1 treatment, every 3 months.

Overall, Polynucleotides are considered a low-downtime treatment and patients are able to return to work and resume normal activities immediately after treatment.

You may experience:

  • Small bumps at injection sites up to 24hrs
  • Mild swelling in the under-eye region, for up to 24hrs
  • Occasional light bruising, which can last a few days (less common)

Aftercare:

  • Avoid makeup for 12–24 hours
  • Avoid strenuous exercise, heat (saunas, hot baths), and alcohol for 24 hours
  • Do not massage the treated area unless advised
  • Keep skin clean and well hydrated
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